The application period for the 2021 course offering is now closed. Applications for the 2022 course offering will be accepted this summer.
Please prepare a single PDF file containing the following elements in the order shown:
- Cover page with your name (first-name last-name), title (including academic rank, if relevant), department, and institution; your mailing address, telephone number, e-mail address; the title of your proposed drug discovery and development project; and the disease area of your project (e.g., epilepsy, stroke, neurodegenerative disease, neuropathic pain, drug addiction, etc.). Please indicate with the appropriate check box whether the therapeutic to be discovered or developed in your proposed project is a small molecule or a biological/non-small molecule (antibody, oligonucleotide, cell therapy, gene therapy, therapeutic vaccine, recombinant protein, blood product, etc.). Please use the cover page in PDF format available for download by clicking the button below.
- Brief drug discovery project proposal exercise. Describe a drug discovery and development project that is of interest to you in a maximum of 2 pages (not including literature citations).This brief synopsis should include discussion of the project background and its rationale, specific aims, and relevant literature citations. Figures may be included but are not required. Please abide by font (11 points or larger) and margin (0.5 inch) specifications that apply to NIH grant applications. The proposal may describe a project that arises from your current work (for example, an ongoing project in basic or clinical neuroscience) or it may be a new concept developed specifically for this application. No preliminary data is expected or required. Your proposed project will serve as the basis for several active engagement activities in which you will participate during the training program.Tips on how to prepare a successful application: This course teaches the principles of neurotherapeutics drug discovery and development. Do not simply re-purpose a basic science grant application. Successful applications will discuss a specific unmet therapeutic need and a strategy to identify new small molecule drugs or biological therapies that could potentially benefit patients. Generally, an in vitro test system or animal model to identify lead candidates will be available, or you will already have identified pre-existing lead molecules of some type even if they are not optimized for the purpose. You don’t need to demonstrate familiarity with the process of drug discovery and development; you will learn this process in the course. This course covers the discovery of traditional small molecule drugs as well as biologic therapies (monoclonal antibody, protein therapy, antisense oligonucleotide, gene therapy, cell therapy, etc.). The course does not teach principles of clinical trials; your application should not focus on research with human subjects. Note: Your application will not be made public. Nevertheless, please do not include any proprietary or confidential material, including proprietary chemical structures.
- NIH format biographical sketch (as described here), 5 pages maximum as per NIH rules. In the personal statement section briefly discuss your academic preparation and research experience and include a description of the reason you would like to participate in this course and your long-term goals.
- Brief note approving your participation if you are a post-doctoral fellow. A brief note from your supervisor approving your participation if you are a post-doctoral fellow, research associate, graduate student, or if you hold a similar type of title.
Your application should consist of a single PDF file, with the cover page as the first page. Include the four other parts of your application in sequence after the cover page. Although not preferred, a Microsoft Word document is acceptable if you cannot prepare a PDF.
The file name of the PDF should be the applicant’s name as follows:
last-name_first-name.pdf, such as Jones_Sally.pdf.
The PDF should be uploaded by dragging the file onto the box below. You may also select a file on your computer.
Applicants will receive notification in due course that their application has been received and is being processed. If you don’t receive a notification, please contact Caroline Foote at the e-mail address given below.
Please be prepared to have a computer (laptop or tablet is acceptable) with microphone and camera to participate in the course.
Questions? Contact Caroline Foote of ASENT at the following e-mail address: firstname.lastname@example.org
Distribution of students in the 2020 course offering. Academic researchers working at universities and non-profit research institution are eligible for the training program. Because of stipulations mandated by the course funding, researchers working in industry are not eligible to apply. The course is directed toward advanced postdoctoral fellows and faculty members. Occasionally, advanced graduate students are accepted.